Down Syndrome: Changing Cardiac Phenotype?
نویسندگان
چکیده
Down syndrome (DS) is the most common chromosomal abnormality, affecting 1 in 700 infants born yearly in the United States.1 The birth prevalence of DS varies internationally among populations, likely due to variations in maternal age, race/ethnicity, use of prenatal screening, and terminations of affected pregnancies.2, 3 Approximately half of all infants born with DS also have a congenital heart defect (CHD), the most common type being atrioventricular septal defect (AVSD), with rates from 30% to 60%.4 In the era of increasing maternal age and pregnancy terminations, 2 it is interesting to investigate if and how the pattern of associated CHDs among infants with DS has changed.
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Congenital Heart Disease in Children with Down syndrome in Kermanshah, West of Iran during 2002 - 2016
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